MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.;UNIVERSITÄTSSPITAL BASEL
发明人:
GENNARO DE LIBERO,MARCO CAVALLARI,PETER H. SEEBERGER,PIERRE STALLFORTH
申请号:
BR112014023193
公开号:
BR112014023193A2
申请日:
2013.03.19
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to the field of synthesizing and biologically evaluating of a novel class of carbohydrate-based vaccines. The new vaccines consist of a multi-modular structure which allows applying the vaccine to a whole variety of pathogenes. This method allows preparing vaccines against all pathogens expressing immunogenic carbohydrate antigens. As conjugation of antigenic carbohydrates to proteins is not required the conjugate vaccine is particularly heat stable. No refrigeration is required, a major drawback of protein-based vaccines.