This invention describes the use of indane acetic acid derivatives which are dual PPAR delta / gamma agonists for the treatment of liver diseases including one or more of the following: NAFLD (Non Alcoholic Fatty Liver Disease) NASH (Non Alcoholic Steatohepatitis) Farber s Disease ACLF (Acute on Chronic Liver Failure) CLF (Chronic Liver Failure) POLT HCV SVR (Post Orthotopic Liver Transplant due to Hepatitis C Virus infection after Sustained Viral Response following anti HCV therapy) Alagille syndrome PFIC (Progressive Familial Intrahepatic Cholestasis) PBC (Primary Biliary Cirrhosis) Primary Sclerosing Cholangitis ADPCLD (Autosomal Dominant Polycystic Liver Disease) Treatment of liver transplant patients with reestablished fibrosis CESD (Cholesteryl Ester Storage Disease) SHTG (Severe Hypertriglyceridemia) HoFH (Homozygous Familial Hypercholesterolemia) HE (Hepatic Encephalopathy) or Alcoholic Liver Disease.
