MIINEA, LILIANA A.,DRAGANOIU, ELENA S.,CHIKHALIKAR, KEDAR V.,CHADAWAR, VIKRANT V.
申请号：
CA3062158
公开号：
CA3062158A1
申请日:
2018.05.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The disclosed technology provides improved drug compositions that provideincreased stability, higher drug loadingpotential, and suitable drug dissolution properties, and methods of making thesame. The composition include: (a) a drug componentcomprising a therapeutically effective amount of a drug； (b) an extendedrelease component comprising a cross-linked polyacrylic acidpolymer that is a carbomer homopolymer, carbomer copolymer, carbomerinterpolymer, polycarbophil or a mixture thereof； and (c)a buffering component comprising a magnesium containing buffering agent；wherein the drug component makes up at least 50% byweight of the composition.
