The present invention discloses a natural broad-spectrum preservative composition containing a citrus grandis fruit extract and its use. The composition mainly comprises a citrus grandis fruit extract, a hydroximic acid, an aromatic alcohol, and one or more polyols. The preservative composition uses a natural citrus grandis fruit extract as a main raw material, which is combined with a hydroxamic acid having a good inhibitory effect on fungi and an aromatic alcohol having a good inhibitory effect on bacteria dissolved in an improved functional solvent, has the characteristics of low irritation and high safety, and not only provides an excellent broad-spectrum bacteriostatic effect, but also improves the performance and values of the product due to the good oxidation resistance of the citrus grandis fruit extract.
