A dry powder inhaler suitable for administration by pulmonary or nasal route, comprising a body (201； 801) of the inhaler and a cartridge (203； 803)； the inhaler comprising: (a) a body (201； 801) of the inhaler comprising a mouth (802), a lower channel inlet (210； 310； 410； 510； 610； 810), a channel (208, 808) inhalation to provide fluid communication between the patient's mouth when coupled with the mouth (802) and the inlet (210； 310； 410； 510； 610； 710； 810) of the lower channel, at least one inlet (818 ) lateral to allow direct air admission from the atmosphere to the interior of the inhalation channel (208, 808)； an opening (204； 804) of the body of the inhaler formed inside and defined between opposite upper (211； 811) and lower walls (812) and opposite side walls (814), said opening (204； 804) presenting the body of the inhaler at least one open end through which the cartridge (203； 803) can be inserted into the opening (204； 804) and which has at least one air inlet opening (815, 816) to admit air into of the opening (204； 804) of the inhaler body, a means (819) for guiding the movement of the cartridge (203； 803) into the opening (204； 804) of the inhaler body relative to the body (201； 801 ) and control its movement from a storage position to an inhalation position； (b) the cartridge (203； 803) being shaped to fit into the opening (204； 804) of the inhaler body and incorporating at least one compartment (205； 305； 405； 505； 605； 705； 805) of powder substantially cylindrical formed therein to transport a powder-based medicament, and at least one vent (206, 209； 306, 309； 406, 409； 506, 509； 606, 609； 709； 806, 809) inlet air； the dust compartment having an outlet (207； 807) that allows fluid communication with the body inhalation channel (208； 808) through the channel inlet (210； 310； 410； 510； 610； 810) lower body and at least one spike (820) to fit with the body guide displacement means (819)； wherein the cartridge (203； 803) can slide into the body (201；
