A procedure for the Administration of a preparation of IgG by intradermal (ID) to a subject in need thereof includes loading with a volume of the preparation of IgG to a Management device ID that includes Needles, the application of the device to a WMD site Contracts in the skin, the use of the device to allow the Dermal Penetration of The Needles.The Administration of the volume of the preparation of IgG at the site of Administration into the skin and withdrawal device of injection. The compositions of a preparation of IgG are for use in the treatment of a disease in a subject in need Of the same by the procedure mentioned above.The disease can be an immunodeficiency.