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PROGRANULIN (PGRN) AND ITS DERIVATIVES FOR DIAGNOSIS AND TREATMENT OF LYSOSOMAL STORAGE DISEASES
专利权人:
Chuanju Liu;Jinlong Jian
发明人:
Chuanju Liu,Jinlong Jian
申请号:
US15116122
公开号:
US20170049855A1
申请日:
2015.02.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides composition and methods for diagnosis and treatment of lysosomal storage diseases and their diagnosis and treatment, including Gaucher's Disease and Tay-Sachs disease, and particularly which utilize progranulin (PGRN), or active PGRN peptides, including atsttrin. The invention also provides animal models of lysosomal storage diseases, including Gaucher's Disease and Tay-Sachs disease, based on or including PGRN mutations including PGRN null mutants and PGRN gene knock outs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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