A brake structure for a wheelchair having a pair of wheels includes: a braking device for braking one of the pair of wheels; a grip to be held by an operator for a moving operation of the wheelchair, the grip including a base fixed to the wheelchair at any position around one axis along a travel direction A of the wheelchair, extending in such a manner as to protrude from the one axis in a radial direction when viewed from the travel direction of the wheelchair, and being mounted rotatably in one direction; and a braking operation section (a brake wire coupling member and a brake wire) for operating the braking device in accordance with the rotation of the grip. Consequently, the load of a braking operation can be reduced, and the ease of a moving operation during the braking operation can be improved.