Benzimidazoledihydrothiadiazinone derivatives (I) and their crystalline forms, tautomers, enantiomers, diastereoisomers, epimers and/or salts, are new. Benzimidazoledihydrothiadiazinone derivatives of formula (I) and their crystalline forms, tautomers, enantiomers, diastereoisomers, epimers and/or salts, are new. R 1alkyl, alkoxyalkyl, alkenyl, alkynyl (all optionally substituted by Y 1), aryl, arylalkyl, aryloxyalkyl, arylalkyloxyalkyl, arylthioalkyl, arylalkylthioalkyl, heteroaryl, heteroarylalkyl, heteroaryloxyalkyl, heteroarylalkyloxyalkyl, heteroarylthioalkyl, heteroarylalkylthioalkyl, cycloalkyl, cycloalkylalkyl, cycloalkyloxyalkyl, cycloalkylalkyloxyalkyl, cycloalkylthioalkyl, cycloalkylalkylthioalkyl, heterocycloalkyl, heterocycloalkylalkyl, heterocycloalkyloxyalkyl, heterocycloalkylalkyloxyalkyl, heterocycloalkylthioalkyl, heterocycloalkylalkylthioalkyl or A-B 1group comprising two cycles A and B 1linked by a bond (where each of the aryl, heteroaryl, cycloalkyl or heterocycloalkyl is optionally substituted by Y 1)； A, B 1aryl, heteroaryl, cycloalkyl or heterocycloalkyl (all optionally substituted by Y 1)； R 2, R 3alkyl, alkoxyalkyl, alkenyl, alkynyl (all optionally substituted by Y 1), aryl, arylalkyl, aryloxyalkyl, arylalkyloxyalkyl, arylthioalkyl, arylalkylthioalkyl, heteroaryl, heteroarylalkyl, heteroaryloxyalkyl, heteroarylalkyloxyalkyl, heteroarylthioalkyl, heteroarylalkylthioalkyl, cycloalkyl, cycloalkylalkyl, cycloalkyloxyalkyl, cycloalkylalkyloxyalkyl, cycloalkylthioalkyl, cycloalkylalkylthioalkyl, heterocycloalkyl, heterocycloalkylalkyl, heterocycloalkyloxyalkyl, heterocycloalkylalkyloxyalkyl, heterocycloalkylthioalkyl, heterocycloalkylalkylthioalkyl (where each of the aryl, heteroaryl, cycloalkyl or heterocycloalkyl is optionally substituted by Y 1) or H； R 4, R 5H or W1； Y 1OH, thio, halo, trifluoromethoxy, trifluoromethyl, alkyloxy, carboxyl, alkoxycarbonyl, carbamoyl, sulfamoyl, nitro, guanidino, amidino, aryl, heteroarylimidazolone, amino or -
