A suture drive system configured to assist in attaching a suture to tissue within a patient, and in at least one application, repairing meniscal tears and shoulder tissue tears is disclosed. The suture drive system may be interchangeable in that the system can be adapted to insert different suture systems into tissue of a patient using the same device. In particular, in one embodiment configured to employ an inside-out suture delivery method, the suture drive system may advance two combinations of push rods and two swaged needles having one or more sutures attached thereto. In another embodiment configured to employ an outside-in suture delivery method, the suture drive system may advance two combinations of push rods and drive shafts to deliver two anchors releasably affixed to the distal ends of the drive shafts into tissue to close an opening in the tissue.