VACCINE COMPOSITION COMPRISING OUTER MEMBRANE PORIN K36 PROTEIN (OMPK36)农业专利-农业专业知识服务系统

发明人:: SUI, LEUNG KEI,萧梁基,蕭樑基,CHANG, FENG YEE,张峰义,張峰義,LIN, YUNG CHUNG,林永崇,林永崇,FUNG, CHANG PHONE,冯长风,馮長風,LIU, YIP MEI,廖叶媚,廖葉媚,CHEN, JIUN HAN,陈俊翰,陳俊翰,TSAI, YU KUO,蔡昱果,蔡昱果,CHONG, POLE CHOI-SING,庄再成,莊再成,LENG, CH

摘要：: The present invention relates a vaccine for vaccinating a mammal to produce an antibody against Enterobacteriaceae infection caused by Klebsiella pneumoniae, Salmonella typhi, or E coli in central nervous system and/or peripheral blood circulation, which comprises administering to the mammal an effective amount of an OmpK36 or its derivatives to the mammal.本發明係關於一種含腸桿菌科外膜孔道蛋白K36(OmpK36)之疫苗,用於免疫哺乳動物之由腸桿菌的肺炎克雷白氏桿菌(Klebsiella pneumoniae)、沙門氏鼠傷寒桿菌(Salmonella typhi)、大腸桿菌引起的中樞神經系統細菌感染及/或周邊血液循環細菌感染,其藉由投藥有效量的外膜孔道蛋白K36(outer membrane porin K36 protein,OmpK36)或其衍生物至哺乳動物。