<;P>;PROBLEM TO BE SOLVED: To provide an adsorption device containing adsorbing material suitably used for adsorbing and eliminating leukocyte and cytokine excessively appearing in blood. <;P>;SOLUTION: This adsorbing material is obtained by coupling hydrophilic amine residue to an insoluble support, and the pore capacity percentage of pores having a pore size ranging from 1 &mu;m to 100 &mu;m is under 30%. As to the hydrophilic amine residue, it is preferable that amino group is quaternary in viewpoint of cytokine adsorption. <;P>;COPYRIGHT: (C)2007,JPO&INPIT