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SiRNA and their use in methods and compositions for inhibiting the expression of the FLAP gene
专利权人:
发明人:
Ana Isabel Jimenez,Covadonga Pañeda,Tamara Martinez
申请号:
US15030169
公开号:
US10017766B2
申请日:
2014.10.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to si RNA molecules and their use in methods and pharmaceutical compositions for inhibiting the expression of the FLAP gene. The invention also relates to the use of said si RNAs molecules in the treatment and/or prevention of an eye condition characterized by increased expression and/or activity of FLAP gene, preferably said eye condition is conjunctivitis and/or an ocular allergy such as seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and giant papillary conjunctivitis.
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