The invention relates to heterocyclic compounds as S1P modulators, pharmaceutical compositions comprising such compounds, and uses thereof in the treatment, alleviation or prevention of diseases or disorders mediated by an S1P receptor.本發明係有關於作為SIP調節劑之雜環化合物;包含該等化合物之藥學組成物;及其等在治療、緩解或預防由一S1P受體所媒介的疾病或疾患之用途。