William W. Bachovchin,Andrew G. Plaut,Daniel J. Drucker
申请号:
US13297522
公开号:
US08513190B2
申请日:
2011.11.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides methods for modification and regulation of type II diabetes by administering to an animal a therapeutically effective amount of an inhibitor of dipeptidylpeptidase IV (DPIV) or a pharmaceutically acceptable salt thereof, where the inhibitor has a Ki for inhibition of DPIV of 10 nM or less and the inhibitor is administered in an amount sufficient to treat type II diabetes but not sufficient to suppress the immune system of the animal.