Pharmaceutical compositions and methods for the treatment of neuropsychological impairment in human patients comprising a central nervous system (CNS) stimulant in a daily low- dosage amount, and a micronutrient composition containing acetyl L-carnitine, L-tyrosine, N-acetyl cysteine, and alpha-lipoic acid. The CNS stimulant and micronutrient components may be in admixture for convenient daily oral administration of a low dosage CNS stimulant and micronutrients in the range of bout 60 - 250 mg acetyl L-carnitine, 50-200 mg L-tyrosine, 60 -250 mg N-acetyl cystein, and 25 - 100 mg alpha-lipoic acid per day.