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Method for producing a bacteriophage mixture, drug, phage mixture and its use in the therapy of antibiotic resistant staphylococci
专利权人:
PHYTOLINE GMBH
发明人:
ROBERT F. MÜLLER
申请号:
BRPI0909330
公开号:
BRPI0909330A2
申请日:
2009.03.13
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Method for preparing a mixture of bacteriophages, with which at least two different bacteriophage strains are separately propagated, comprises: (a) growing a Staphylococcusstrain with each strain of the bacteriophage, which can lyse staphylococci, in a preculture; (b) further propagating in a main culture; (c) subsequently purifying; and (d) subsequently mixing the various strains, where the used mixture of bacteriophage contains at least two different serotypes of bacteriophages that specifically lyse the bacteria of the species Staphylococcus. Independent claims are included for: (1) a phage mixture, obtained by the above method, comprising phages that have specific activity of at least 10 8>;plaque forming units per mu g of protein; and (2) a medicament comprising the phage mixture. ACTIVITY : Antibacterial. MECHANISM OF ACTION : None given.
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中国工程科技知识中心
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