THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人:
Katri TYPPO,Fayez K. GHISHAN,Pawel R. KIELA
申请号:
US15308286
公开号:
US20170053081A1
申请日:
2015.04.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention the present invention provides methods and materials related to the characterization of intestinal barrier function, and related methods for preventing and/or treating intestinal barrier dysfunction. In particular, the present invention provides methods and materials for characterizing intestinal barrier function within mammals (e.g., humans) through determining the level, presence, and/or frequency of biomarkers for intestinal function (e.g., functional enterocyte mass, enterocyte integrity, paracellular tight junction function, gut inflammation) within a biological sample.