ISOQUINOLINES AS INHIBITORS OF HPK1

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专利权人:

Inc.;Genentech

发明人:

Bryan Chan,Joy Drobnick,Lewis Gazzard,Timothy Heffron,Jun Liang,Sushant Malhotra,Rohan Mendonca,Naomi Rajapaksa,Craig Stivala,John Tellis,Weiru Wang,BinQing Wei,Aihe Zhou,Matthew W. Cartwright,Michael

申请号：

US15942333

公开号：

US20180282282A1

申请日:

2018.03.30

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibitng HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/