Michael Caulfield,Albert Cupo,Hansi Dean,Simon Hoffenberg,C. Richter King,P. J. Klasse,Andre Marozsan,John P. Moore,Rogier W. Sanders,Andrew Ward,Ian Wilson,Jean-Philippe Julien
申请号：
US14072209
公开号：
US09738688B2
申请日:
2013.11.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present application relates to novel HIV-1 envelope glycoproteins, which may be utilized as HIV-1 vaccine immunogens, and antigens for crystallization, electron microscopy and other biophysical, biochemical and immunological studies for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions, which are formulated into the vaccines of the present invention.
