Márcia Rogéria DE ALMEIDA,Abelardo Silva JUNIOR,Juliana Lopes Rangel FIETTO,Gustavo Costa BRESSAN,Rafael Locatelli SALGADO,Thiago Souza ONOFRE,Mariana Costa FAUSTO,Pedro Marcus Pereira VIDIGAL,Sthefan
申请号：
US14763121
公开号：
US20160000897A1
申请日:
2014.01.23
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to the preparation of the recombinant antigen of the viral capsid of Porcine circovirus 2 (PCV-2) and modifications thereof, upon expression in a prokaryotic system, purification in the monomer form, recovery of virus-like particles (VLPs) and their use in vaccine formulations, diagnostic kits and a system for quantifying in vaccine lots of the PCV-2 antigen by means of a capture ELISA assay. The antigens and vaccine formulations can be used in animals immunization in programs for combatting PCV-2-associated diseases in conventional swine breeding systems, and represent alternatives to the commercially available vaccines. The ELISA kit can be used for testing the quality of commercial and/or experimental vaccines against PCV-2.
