RAMSEY, EUAN,TAYLOR, ROBERT JAMES,WILD, ANDRE,LEAVER, TIM,WALSH, COLIN
申请号：
CA2918541
公开号：
CA2918541A1
申请日:
2014.07.25
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Methods and devices for manufacturing polymer particles containing a therapeutic material and polymer conjugate particles comprising (a) introducing a first stream comprising a first solvent into a channel, wherein the channel has a first region adapted for flowing one or more streams introduced into the channel and a second region for mixing the contents of the one or more streams (b) introducing a second stream comprising polymer conjugate in a second solvent into the channel to provide first and second streams flowing in the channel (c) flowing the one or more first streams and the one or more second streams from the first region of the channel into the second region of the channel (d) mixing of the contents of the one or more first streams and the one or more second streams flowing in the second region of the channel to provide a third stream comprising polymer conjugate nanoparticles.
