WONG, Lyanne M.,FALLON, Jaymille,GOSS, Monica Michelle,GU, Jian Hua,GHATTYVENKATAKRISHNA, Pavan K.,BRYCH, Stephen Robert
申请号：
PE2019002120
公开号：
PE20200343A1
申请日:
2018.04.27
申请国别(地区):
PE
年份:
2020
代理人:
摘要：
1. This specification describes the water pharmacological formula, including dibenzodiazodiphenyl or other monoclonal anti human RANKL antibody or part thereof, as well as pH value characteristics, tampon system and amino acid polymer inhibitor. It also describes an introduction to a formula, such as in a single-purpose vial, a single-purpose syringe, or a glass container, a method of formula and articles for the prevention or treatment of diseases, and a related toolkit.En la presente se describen formulaciones farmaceuticas acuosas que comprenden denosumab u otro anticuerpo monoclonal anti-RANKL humano o parte de este, y caracteristicas de pH, sistemas tampon e inhibidores de agregacion de aminoacidos. Tambien se describe una presentacion de la formulacion para su uso, por ejemplo, en un vial de unico uso, una jeringa de unico uso, o un recipiente de vidrio, metodos de uso de las formulaciones y articulos para prevenir o tratar enfermedades, y kits relacionados.
