MENNE, TORKIL,SELMER, JOHAN,LANGE, JESPER,GEORGIOU, MICHELLE,WHEELER, DEREK,EVANS, DAVID
申请号：
CA3026620
公开号：
CA3026620A1
申请日:
2017.06.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
There is provided a topical formulation comprising a nucleophile, such as amino acids and most polypetides and/or a derivative thereof, for use in the treatment or prevention of itchy dry skin caused by urea, such as in uremic pruritus, of a subject. The amino acid may be histidine and the derivative may be a histidine degradation product, a peptide of histidine, a peptide of histidine and one or more additional amino acids, and a pharmaceutically- acceptable salt of histidine.
