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Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same
专利权人:
Zibo Li
发明人:
Zibo Li,Francois P. Gabbai,Peter S. Conti,Todd W. Hudnall,Tzu-Pin Lin,Shuanglong Liu,Chiun-Wei Huang
申请号:
US13549309
公开号:
US09987380B2
申请日:
2012.07.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof:wherein R1-R7 may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
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