Poulton, Lynn Dorothy,Clarke, Adam,Pow, Andrew James,Tamvakis, Debra,Kopsidas, George,Doyle, Anthony Gerard,Jennings, Philip Anthony,Pollard, Matthew
申请号:
AU2012315474
公开号:
AU2012315474A1
申请日:
2012.09.28
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The present disclosure also provides uses of the TL1a-binding proteins.