THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;INOVIO PHARMACEUTICALS, INC.
发明人:
WEINER, DAVID,LANG, KRYSTLE,YAN, JIAN,DRAGHIA-AKLI, RUXANDRA,KHAN, AMIR
申请号:
EP11874560
公开号:
EP2771035A4
申请日:
2011.10.24
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Improved anti-HCV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HCV genotype 1a, including for example, NS4B, NS5A and NS5B. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HCV are disclosed.