In an embodiment herein, an aortopulmonary stimulation device is provided including a first electrode for placement on or in the aorta, and a second electrode for placement on or in the pulmonary artery. The embodiment includes a control unit associated with the first and second electrodes for delivering electrical stimulation to the first and second electrodes, wherein the stimulation is delivered to both the first electrode and the second electrode, or to the first electrode or the second electrode to reduce afterload.