Von Wilebrand Factor variants having improved Factor VIII binding affinity

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专利权人:

CSL Behring GmbH

发明人:

Schulte, Stefan,Weimer, Thomas,Hofmann, Kay

申请号：

AU2013200843

公开号：

AU2013200843B2

申请日:

2013.02.15

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

#$%^&*AU2013200843B220150917.pdf#####ABSTRACT 5 Von Willebrand Factor variants having improved Factor Vill binding affinity The present invention relates to a polypeptide comprising a modified von Willebrand Factor (VWF) having a higher Factor Vill binding affinity than non-modified VWF, its 10 pharmaceutical use and method of its preparation.

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