COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE

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专利权人:

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

发明人:

SAGE, PETER T.,SHARPE, ARLENE H.

申请号：

CA3005899

公开号：

CA3005899A1

申请日:

2016.11.23

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The invention provides methods of modulating follicular regulatory T (TFR) cell- mediated immune responses and the use of those methods in the treatment of diseases or conditions such as viral, bacterial, pathogenic, or fungal infections or cancer. Such methods provide for boosting of antibody production through the use of IL-21 to overcome TFR cell suppression of antibody production.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/