A kind of dronedarone solid dispersion and preparation method thereof, for the solid dispersions by forming as the dronedarone of active constituent or its pharmaceutically acceptable salt and carrier material, the carrier material is selected from or mixtures thereof povidone, copolyvidone, hydroxypropyl cellulose.一種决奈達隆固體分散體及其製備方法,所述固體分散體由作爲活性成分的决奈達隆或其藥學上可接受的鹽和載體材料組成,所述載體材料選自聚維酮、共聚維酮、羥丙基纖維素或其混合物。