ANDREOLETTI, GILBERT,BELIERES, MICHEL,NARDOUX, PASCAL,MOULIN, JEAN PAUL,MONTALETANG, ANNE,BOURDET, PATRICK
申请号:
PL08717921
公开号:
PL2125620T3
申请日:
2008.03.18
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The invention relates to a process for producing 228Th from a natural thorium salt, which comprises in succession: a) the separation of the radium from the other radioelements present in this salt, by at least one coprecipitation of the radium by barium sulphate, this coprecipitation comprising: i) the addition of sulphuric acid and a barium salt to an aqueous solution of said natural thorium salt in order to form a barium-radium sulphate coprecipitate and ii) the separation of the coprecipitate from the medium in which it has formed; b) the extraction of the thorium 228 coming from the decay of radium 228 from the coprecipitate thus separated; and, optionally c) the purification and concentration of the 228Th thus extracted. Applications: manufacture of radiopharmaceutical products useful in nuclear medicine, in particular in radioimmunotherapy for the treatment of cancers and AIDS.