Andrew J. Nelson;Richard D. Holly;Steven D. Hughes
发明人:
Andrew J. Nelson,Steven D. Hughes,Richard D. Holly
申请号:
US13535832
公开号:
US20120294798A1
申请日:
2012.06.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods for treating mammals with cancer using molecules that have an IL-21 functional activity are described. The molecules having IL-21 functional activities include polypeptides that have homology to the human IL-21 polypeptide sequence and proteins fused to a polypeptide with IL-21 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer therapeutics.