PRÉPARATION POUR UN DIAGNOSTIC PAR RÉSONANCE MAGNÉTIQUE DE MALADIES ONCOLOGIQUES CONTENANT DU 3-O-MÉTHYLGLUCOSE DEUTÉRÉ ET MÉTHODE DE DIAGNOSTIC UTILISANT CE PRODUIT
The invention relates to medicine, namely to the means for magnetic resonance imaging of the oncological diseases. For this purpose, the diagnostic agent and the diagnostic method based on the use of the diagnostic agent is developed, which is based on a deuterated derivative of 3-O-methylglucose or a mixture of at least two different deuterated derivatives of 3-O-methylglucose. The method of the invention involves performing magnetic resonance imaging and/or magnetic resonance spectroscopy at the frequency of deuterium nuclei after administration of the diagnostic medication after a time sufficient for accumulation of the diagnostic medication in the tumor tissue of a subject for receiving, respectively, MR images and/or MR spectra.The proposed method allows diagnosing oncological diseases with high informational content.
