The invention generally relates to intracavitary medical devices and methods for using the devices. In one aspect, the devices comprise: a tube comprising a longitudinal body having opposed proximal and distal ends, and at least three lumens extending there between; and an expandable balloon region located at the distal end of the tube; wherein at least one lumen comprises at least one of: a drainage lumen which opens at a portion of the distal end of the tube and configured to allow fluid communication from a body cavity into the drainage lumen, an inflation lumen connected to an interior of the balloon region and configured to enable passage of a distending fluid to control expansion and contraction of the balloon region, and an instillation lumen which opens at a portion of the distal end of the tube and configured to allow a fluid to be introduced from the instillation lumen into the body cavity.