A method for preventing and/or treating renal tissue injury of a subject, comprising administering an effective amount of plasminogen to a subject. The subject is at the risk of suffering renal tissue injury, is suspected to suffer renal tissue injury, or suffers renal tissue injury. Also provided are a drug, a pharmaceutical composition, a product, and a kit comprising plasminogen and used for preventing and/or treating renal tissue injury and related diseases thereof of a subject.
