A first aspect of the present invention is directed to a surface treatment for elastomeric articles such as medical gloves, comprising a water-based coating formulation and antimicrobial agent(s) embraced therein in an essentially powder-free composition coating. A second aspect of the present invention is directed to a water-based coating formulation for elastomeric articles such as gloves comprising at least one non-volatile water-soluble antimicrobial agent in a controlled-release matrix comprising a blend of a hydrophilic polymer and a hydrophobic component. The controlled-release matrix/blend requirements include: compatibility with the antimicrobial agent, formation of a reservoir of antimicrobial agent, coating film flexibility and lower water-solubility than the antimicrobial agent. A third aspect of the present invention is directed to a method for treating medical gloves comprising dipping, spraying, tumbling or other means for applying to the glove surface a composition to provide medical gloves with sustainable antimicrobial activity.