Vivekananda M. Vrudhula;Richard A. Hartz;Vijay T. Ahuja;Joanne J. Bronson
发明人:
Richard A. Hartz,Vijay T. Ahuja,Vivekananda M. Vrudhula,Joanne J. Bronson
申请号:
US13052458
公开号:
US08372847B2
申请日:
2011.03.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatment of psychiatric disorders and neurological diseases including depression, anxiety related disorders, irritable bowel syndrome, addiction and negative aspects of drug and alcohol withdrawal, and other conditions associated with CRF.