Technion Research & Development Foundation Limited
发明人:
Gera Neufeld
申请号:
US15017700
公开号:
US09617347B2
申请日:
2016.02.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.