HEXTALL, PATRICK,MIDWOOD, KIM SUZANNE,CULBERT, ERIC
申请号:
CA3013168
公开号:
CA3013168A1
申请日:
2017.02.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present disclosure relates fully antibodies and binding fragments, to a Tenascin, in particular the FBG domain of a Tenascin, which are potentially less immunogenic than the parent antibody. The disclosure also relates to composition comprising the antibody or binding fragment and use of any one of the same for diagnosis, prognosis and/or treatment of disorders such as those associated with chronic inflammation. The disclosure further provides methods of making said antibodies.