The invention relates to solid forms of certain N-(pyrimidinyloxy)acrylamide derivatives that are useful in the treatment of proliferation and immunological disorders and other diseases related to the dysregulation of kinases including EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3 (D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK. The invention provides methods of making these materials and their salts and polymorphs, and intermediates for preparing these materials, as well as pharmaceutical compositions comprising these materials. The solid forms and pharmaceutical compositions comprising them are useful to treat conditions including a proliferation disorder, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye, rheumatoid arthritis, or lupus.本發明係關於某些N-(嘧啶氧基)丙烯醯胺衍生物之固體形式，其適用於治療與激酶調節異常相關之增生及免疫病症及其他疾病，該等激酶包括EGFR (包括HER)、Alk、PDGFR、BLK、BMX/ETK、BTK、FLT3 (D835Y)、ITK、JAK1、JAK2、JAK3、TEC及TXK。本發明提供製造此等材料及其鹽及多晶型物之方法，及製備此等材料之中間物，以及包含此等材料之醫藥組合物。該等固體形式及包含其之醫藥組合物適用於治療包括增殖病症、腫瘤、發炎疾病、自體免疫疾病、牛皮癬、乾眼症、類風濕性關節炎或狼瘡之病況。
