George Q. Daley,Alena V. Yermalovich,Jihan K. Osborne
申请号：
US16622130
公开号：
US20200123549A1
申请日:
2018.06.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Described herein are methods of prolong or reactivating organogenesis in a subject in need thereof (e.g., a subject that has impaired organ function such as a prematurely born infant). The methods comprises increasing the expression or activity of Lin28A or Lin28B proteins, inhibiting the expression or activity of let-7 family microRNAs, and/or inhibiting the expression or activity of Dis3L2 exonuclease.
