DÉRIVÉS INDANONE, LEURS ISOMÈRES OPTIQUES OU LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES, LEUR PROCÉDÉ DE PRÉPARATION, ET DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT EN TANT QUE PRINCIPE ACTIF POUR PRÉVENIR OU TRAITER DES MALADIES VIRALES
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D;KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人:
JUNG, YOUNG SIK,LEE, CHONG KGO,KIM, HAE SOO,JEONG, HEE CHUN,KIM, PIL HO,HAN, SOO BONG,NEYTS, JOHAN,THIBAUT, HENDRIK JAN,SHIN, JIN SOO
申请号：
EP12800577
公开号：
EP2722042A4
申请日:
2012.06.18
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention relates to a novel indanone derivative, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient for preventing or treating viral diseases. The indanone derivatives according to the present invention not only have low cyto-toxicity, but can also demonstrate utility as pharmaceutical compositions for preventing or treating viral diseases such as:； polio, viral paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-mouth disease, blistering diseases, hepatitis A, myositis, myocarditis, pancreatitis, viral diabetes, epidemic myalgia, encephalitis, flu, herpes angina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis, otitis media, and the like, since excellent antiviral activity against picornaviruses such as Coxsackie virus, enterovirus, echovirus, polio virus, rhinovirus, and the like, have been demonstrated.
