The invention provides for a medical system (201), wherein the medical system comprises a cartridge (100) and an inserter (200), wherein the cartridge comprises: a housing (103) with an interior volume (104), wherein the housing comprises a first guiding structure (106) within the interior volume; a cradle (112) for mounting a medical appliance, wherein the cradle comprises a subcutaneous element, wherein the cradle is within the interior volume, wherein the cradle comprises an adhesive layer for attaching to an exterior surface (400) of a subject, wherein the cradle further comprises an insertion needle, wherein the insertion needle being configured for being actuated to insert the subcutaneous element into the subject. The inserter comprises: a second guiding structure (206) for mating with the first guiding structure, wherein the first guiding structure and the second guiding structure are configured for guiding a portion (203) of the inserter into the interior volume along an guiding path (110), wherein the portion of the inserter is configured for removably attaching to the cradle when guided into the interior volume; and an insertion mechanism for actuating the insertion needle to insert the subcutaneous element into the subject.