SHIH, NENG YAO,施能耀,LIU, KO JIUNN,刘柯俊,劉柯俊,CHEN, LI TZONG,陈立宗,陳立宗,HUNG, WEN CHUN,洪文俊,CHEN, YUN CHANG,陈永昌,陳永昌,HSIAO, KUAN CHUNG,萧冠中,蕭冠中,SHEN, SA TAI,沈三泰
申请号：
TW108109596
公开号：
TW202003035A
申请日:
2019.03.20
申请国别(地区):
TW
年份:
2020
代理人:
摘要：
An isolated antibody, comprising heavy chain complementary determining regions CDR1, CDR2, and CDR3 from a heavy chain variable region sequence having SEQ ID NO: 1 or 3； light chain complementary determining regions CDR1, CDR2, and CDR3 from a light chain variable region sequence having SEQ ID NO: 2 or 4； wherein the antibody binds specifically to both vascular endothelial growth factor receptor-2 (VEGFR2) and vascular endothelial growth factor receptor-3 (VEGFR3).發明係關於一種單離抗體，包含重鏈互補決定區CDR1、CDR2、CDR3與輕鏈互補決定區CDR1、CDR2、CDR3，其重鏈互補決定區係包含於具有SEQ ID NO: 1或3之重鏈可變區序列，輕鏈互補決定區係包含於具有SEQ ID NO: 2或4之輕鏈可變區序列，該抗體可與血管內皮生長因子受體-2 (vascular endothelial growth factor receptor-2, VEGFR2)及VEGFR3特異性結合。
