A device for closing an opening formed in a patients body without the use of sutures. The device includes a patch formed of a flexible that can be positioned between an open position and an at least partially closed position. The body has a plurality of sharp protrusions formed along the first face for securely attaching the flexible body to a target structure within the patients body in which the opening is formed such that the flexible body extends across and closes the opening. The device further includes an instrument for delivering the patch to an inner face of a structure in which the opening is formed. The instrument has a first member that mates with the patch for securely, yet releasably, attaching the patch to the instrument to allow delivery of the patch.
