Formulations for topical compositions which may be used to deliver drugs. The formulations may be used with a wearable drug delivery device for transdermal delivery. The composition may comprise a clay carrier such as kaolin and/or halloysite, loaded with one or more target compositions. The composition may comprise about 5 to about 15 percent by weight kaolin； about 5 to about 15 percent by weight oil carrier； about 2 to about 3 percent by weight essential oil； about 6.5 to about 26 percent by weight emollient； about 15 to about 20 percent by weight aloe vera barbadensis juice gel； about 0.9 percent to about 5 percent by weight thickening agent； about 0.1 percent to about 5 percent by weight stabilizer； about 2 percent to about 8 percent by weight surfactant； about less than 1 percent by weight target compound； about 0.35 to about 1.8 percent by weight preservative； and about 1 percent to about 5 percent by weight water.
