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SUSPENSION AQUEUSE DE PROTÉINE
专利权人:
Terumo Kabushiki Kaisha
发明人:
申请号:
EP14858535.9
公开号:
EP3064213A4
申请日:
2014.10.28
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
It is an object of the present invention to provide, for a wide range of proteins, an aqueous suspension preparation containing a protein complex that can be concentrated and is high in stability. The present invention is an aqueous suspension preparation comprising an aqueous suspension in which a protein and a polyamino acid that have surface charge in a buffer form a complex to be suspended in the buffer, wherein the protein can be concentrated by removing at least part of water from the complex-containing aqueous suspension, and in the complex, the protein has at least one of shaking stress resistance, fluidity enhancement, oxidation resistance, thermal stability, and aggregation inhibitory properties.
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