Gareth Neil Brace,Rose Elizabeth Chappell,Hervé Jean Claude Deboves,Anne Marie Foley,Gregory Foulkes,Elizabeth Pearl Jones,Fabien Claude Lecomte,Joanna Rachel Quincey,Monika-Sarah Elisabeth Dorothea S
申请号:
US16619573
公开号:
US20200138797A1
申请日:
2018.06.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A series of substituted spirocyclic 2-oxoindoline derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.