PROBLEM TO BE SOLVED: To provide a keratin dispersant and an agent for inhibiting a dermatological change, which act on keratin in keratinocytes to prevent a feeling of dry skin and a stretched feeling.SOLUTION: The keratin dispersant and the agent for inhibiting a dermatological change consists of a compound represented by general formula (1a) or (1b) (where R1 represents a hydrogen atom or a C1-4 alkyl group, R2 represents a hydrogen atom, a carboxyl group (R5 represents a C1-4 alkyl group and R6 represents a hydrogen atom, a C1-4 alkyl group, an amino group, a dipeptide group, or a tripeptide group), R3 and R4 each represent a hydrogen atom or a hydroxyl group, and n represents 1, 2, or 3).SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】角質細胞のケラチンに作用して、皮膚の乾燥感やつっぱり感を抑制するケラチン分散剤、皮膚形状変化抑制剤を提供する。【解決手段】一般式(1a)又は(1b)(式中、R1は、水素原子又は炭素数1~4のアルキル基を示し、R2は、水素原子、カルボキシル基、(R5は、炭素数1~4のアルキル基を示し、R6は、水素原子、炭素数1~4のアルキル基、アミノ酸基、ジペプチド基又はトリペプチド基を示す)を示し、R3及びR4は、同一又は異なって、水素原子又はヒドロキシル基を示し、nは、1、2又は3を示す)で表される化合物から成るケラチン分散剤、皮膚形状変化抑制剤。【選択図】なし
